

HY-146974 · 50 mg
MedChemExpress · Cat: HY-146974
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medchemexpress.com/pde4-in-9.htmlDescription
PDE4-IN-9 Compound 5j is a potent inhibitor of PDE4. PDE4-IN-9 exhibits lower IC50 value 1.4 ?M against PDE4 than parent rolipram 2.0 ?M in in vitro enzyme assay. PDE4-IN-9 also displays good in vivo activity in animal models of asthma/COPD and sepsis induced by LPS.







