GENERAL CATALOGUE
PDE5-IN-3
HY-131710 · 50 mg
MedChemExpress · Cat: HY-131710
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Manufacturer product page
medchemexpress.com/pde5-in-3.htmlCatalog No: HY-131710
CAS No: 2538149-57-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
PDE5-IN-3 compound 11j is a potent PDE5 inhibitor with an IC50 of 1.57 nM. PDE5-IN-3 shows moderate EGFR inhibition with IC50 of 5.827 AAasAasAAmuM. PDE5-IN-3 significantly inhibits the Wnt/?-catenin pathway IC50=1286.96 ng/mL . PDE5-IN-3 induces the intrinsic apoptotic mitochondrial pathway in HepG2 cells. PDE5-IN-3 has strong antitumor activity.
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