PDGFRA Mouse Monoclonal Antibody

Description

EnkiLife offers the PDGFRA Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for ICC,ELISA application. Alternative Names of Immunogen: CD140A; PDGFR2; PDGFR-2; RHEPDGFRA. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ICC 1:200-1:1000,ELISA 1:5000-1:20000 Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factorrfamily. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factorrbound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composedrof both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene playsra role in organ development, wound healing, and tumor progression. Mutations in this gene have been associatedrwith idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a varietyrof other cancers. Research Area: PI3K-Akt signaling pathway,Hippo signaling pathway