PDGFRB Mouse Monoclonal Antibody

Description

EnkiLife offers the PDGFRB Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for ELISA,FC application. Alternative Names of Immunogen: IMF1; IBGC4; JTK12; PDGFR; CD140B; PDGFR1; PDGFR-1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. Research Area: PI3K-Akt signaling pathway,MAPK signaling pathway,Hippo signaling pathway