PDK4 Mouse Monoclonal Antibody

Description

EnkiLife offers the PDK4 Mouse Monoclonal Antibody. This antibody reacts with Human, Mouse, Rat species and is suitable for WB application. Alternative Names of Immunogen: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, PDK4, PDHK4. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: This gene is a member of the PDK/BCKDK protein kinasefamily and encodes a mitochondrial protein with a histidine kinasedomain. This protein is located in the matrix of the mitrochondriaand inhibits the pyruvate dehydrogenase complex by phosphorylatingone of its subunits, thereby contributing to the regulation ofglucose metabolism. Expression of this gene is regulated byglucocorticoids, retinoic acid and insulin.