GENERAL CATALOGUE
Pefloxacin
HY-B0147 · 5 mg
MedChemExpress · Cat: HY-B0147
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Catalog No: HY-B0147
CAS No: 70458-92-3
Category: Anti-infection
Pack Size: 5 mg
Brand: MedChemExpress
Description
Pefloxacin Pefloxacinium is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 ?g/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.