GENERAL CATALOGUE
Petasin
HY-N10612 · 50 mg
MedChemExpress · Cat: HY-N10612
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medchemexpress.com/petasin.htmlCatalog No: HY-N10612
CAS No: 26577-85-5
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
Petasin inhibits adipogenesis in cell 3T3-F442A with an IC50 of 0.95 ?M. Petasin inhibits the expression of lipid synthesis factors ACC1, FAS and SCD1 by inhibiting transcription factors PPAR? and C/EBP?, as well as targeting TRPA1 and TRPV1 channels . Petasin inhibits mitochondrial complex I, thereby inhibiting tumor growth and metastasis. Petasin activates AMPK signaling pathway, participating in regulation of glucose and lipid metabolism. Petasin is orally active.
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