Petiline

Description

Petiline is a steroidal alkaloid found in Petilium raddeanum, acting as a selective antagonist of M cholinergic receptors. Petiline exerts anticholinergic effects e.g., reducing vagal influence on the heart by competitively blocking M cholinergic receptors, and also has central excitatory, cardiotonic, and spasmolytic activities. Petiline is promising for research of cholinergic system-related diseases e.g., arrhythmia, intestinal spasm .