PEX19 (2Y10) Rabbit Monoclonal Antibody

Description

EnkiLife offers the PEX19 (2Y10) Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB,ICC/IF,FC,IP application. Alternative Names of Immunogen: HK33; PBD12A; Peroxin 19; PEX19; PMP1; PMPI; PXF; PXMP1;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:5000,ICC/IF 1:50-1:100,FC 1:10-1:100,IP 1:10-1:100 Background: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.