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Pexidartinib, CSF1R inhibitor
ab254454 · 5 mg
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Catalog No: ab254454
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 417.8 Da, Purity >98 %. Potent MCSF Receptor CSF1R inhibitor IC50 = 13 nM . Also inhibits Kit IC50 = 16 nM and Flt3 IC50 = 160 nM . Highly selective IC50 1 muM against a panel of over 200 kinases. Inhibits MCSF Receptor-dependent proliferation 0.1 - 0.44 muM in cell models. Inhibits glioblastoma invasion in mouse xenograft models.
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