GENERAL CATALOGUE
Pexidartinib hydrochloride
HY-16749A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-16749A
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medchemexpress.com/pexidartinib-hydrochloride.htmlCatalog No: HY-16749A
CAS No: 2040295-03-0
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Pexidartinib hydrochloride PLX-3397 hydrochloride is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor CSF1R or M-CSFR and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity.