GENERAL CATALOGUE
Pexidartinib hydrochloride (Standard)
HY-16749AR · 5 mg
MedChemExpress · Cat: HY-16749AR
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Catalog No: HY-16749AR
CAS No: 2040295-03-0
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Pexidartinib hydrochloride Standard is the analytical standard of Pexidartinib hydrochloride . This product is intended for research and analytical applications. Pexidartinib hydrochloride PLX-3397 hydrochloride is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor CSF1R or M-CSFR and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity.
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