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PF-04634817
GENERAL CATALOGUE

PF-04634817

HY-117621 · 50 mg

MedChemExpress · Cat: HY-117621

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medchemexpress.com/pf-04634817.html
Catalog No: HY-117621
CAS No: 1228111-63-4
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress

Description

PF-0463481 is a potent and orally active dual CCR2/CCR5 antagonist with comparable human and rodent CCR2 potency rat IC50=20.8 nM , and displays 10-20 fold less rodent CCR5 potency rat IC50=470 nM . PF-0463481 is safe and well-tolerated and has the potential for the study of diabetic nephropathy.

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