PF-543 Citrate

Name: PF-543 Citrate
Brand: MedChemExpress

HY-15425A · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-15425A

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Manufacturer product page

medchemexpress.com/PF-543-Citrate.html

Catalog No: HY-15425A

CAS No: 1415562-83-2

Category: Apoptosis

Pack Size: Free Sample (0.1 - 0.2 mg)

Brand: MedChemExpress

Description

PF-543 Citrate Sphingosine Kinase 1 Inhibitor II Citrate is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 Citrate is >100-fold selectivity for SPHK1 over SPHK2. PF-543 Citrate is an effective potent inhibitor of sphingosine 1-phosphate S1P formation in whole blood with an IC50 of 26.7 nM. PF-543 Citrate induces apoptosis, necrosis, and autophagy.