GENERAL CATALOGUE
PF-7006
HY-164519 · 50 mg
MedChemExpress · Cat: HY-164519
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medchemexpress.com/pf-7006.htmlCatalog No: HY-164519
CAS No: 2771955-09-8
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
PF-7006 is an Mps1 kinase inhibitor with a Ki value of 0.27 nM and an IC50 value of 2.5 nM. PF-7006 interferes with cell cycle checkpoints by inhibiting the catalytic activity of Mps1, reducing histone H3 levels, and shortening the duration of mitosis, leading to apoptosis in cancer cells. Combined use of PF-7006 with Palbociclib HY-50767 increases cancer cell tolerance to PF-7006. PF-7006 can be used for breast cancer research.