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PFI-3, bromodomain and SMARCA4 inhibitor
ab223602 · 5 mg
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Catalog No: ab223602
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 321.4 Da, Purity >98 %. Potent and selective inhibitor of Polybromo Kd = 48 nM and SMARCA4 Kd = 89 nM . Also inhibits SMARCA2. Displays high specificity for Family VIII bromodomains. PFI-3 displays selectivity against a range of other kinases. In a panel of 103 receptors and enzymes, activity was observed only against 4 GPCRs. At a concentration of 1 muM, PFI-3 accelerates FRAP recovery in cells.
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