GENERAL CATALOGUE
PFK-158
HY-12203 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-12203
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medchemexpress.com/PFK-158.html
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Catalog No: HY-12203
CAS No: 1462249-75-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistins resistance to bacteria.
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