GENERAL CATALOGUE
PHA-665752
HY-11107 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-11107
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Catalog No: HY-11107
CAS No: 477575-56-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
PHA-665752 is a selective, ATP-competitive, and active-site inhibitor of the catalytic activity of c-Met kinase Ki=4 nM; IC50=9 nM . PHA-665752 exhibits >50-fold selectivity for c-Met compared with a panel of diverse tyrosine and serine-threonine kinases. PHA-665752 induces apoptosis and cell cycle arrest, and exhibits cytoreductive antitumor activity.