Phendioxan

Description

Phendioxan is a compound with binding activity at the ? 1 -adrenaline receptor subtype. The facilitated membrane diffusion of phendioxan is thought to be associated with improved ? 1d -AR affinity. Docking simulations of phendioxan at biological targets supported the stoichiometric analysis and revealed the importance of polar, electrostatic, hydrophobic, and shape effects of its phenoxy terminal orthogonal substituents on ligand binding.