Phospho-ATF4 (Ser219) Rabbit Polyclonal Antibody

Description

EnkiLife offers the Phospho-ATF4 (Ser219) Rabbit Polyclonal Antibody. This antibody reacts with Human species and is suitable for WB application. Alternative Names of Immunogen: Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: ATF4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress. Research Area: Epigenetics and Nuclear Signaling