Phospho-BRAF (Thr401) Rabbit Monoclonal antibody

Description

EnkiLife offers the Phospho-BRAF (Thr401) Rabbit Monoclonal antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IP application. Alternative Names of Immunogen: BRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IP 1:20-1:50 Background: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations. Research Area: Cell Biology