Phospho-CDC6 (Ser106) Rabbit Monoclonal Antibody

Description

EnkiLife offers the Phospho-CDC6 (Ser106) Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB application. Alternative Names of Immunogen: CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.Cdc6 has recently been shown to play an important role in the intra-S-phase p21 Waf1/Cip1-dependent DNA damage response. Both cdc6 and CDT1 are degraded by the ubiquitin proteasome pathway in response to DNA damage associated with re-replication. Research Area: Epigenetics and Nuclear Signaling