Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody

Description

EnkiLife offers the Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB application. Alternative Names of Immunogen: HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases. Research Area: Epigenetics and Nuclear Signaling