Phospho-LEF1 Mouse Monoclonal Antibody

Description

EnkiLife offers the Phospho-LEF1 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ELISA application. Alternative Names of Immunogen: LEF-1; TCF10; TCF7L3; TCF1ALPHA. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000 Background: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. Research Area: Wnt signaling pathway,Hippo signaling pathway