Phospho-Leptin Receptor (Tyr1141) Rabbit Polyclonal Antibody

Description

EnkiLife offers the Phospho-Leptin Receptor (Tyr1141) Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,ELISA application. Alternative Names of Immunogen: Leptin receptor; LEP-R; HuB219 OB receptor; OB-R; CD295; LEPR; DB; OBR. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ELISA 1:5000-1:20000 Background: On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity). Research Area: Signal Transduction