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Phosphodiesterase-IN-2
GENERAL CATALOGUE

Phosphodiesterase-IN-2

HY-161663 · 50 mg

MedChemExpress · Cat: HY-161663

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Catalog No: HY-161663
CAS No: 3047610-96-5
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress

Description

Phosphodiesterase-IN-2 Compound C7 is a selective, orally active inhibitor for phosphodiesterase 10A PDE10A , with an IC50 of 11.9 nM. Phosphodiesterase-IN-2 improves the stability of liver microsomes, and lowers BBB permeability. Phosphodiesterase-IN-2 exhibits good pharmacokinetic characters, and attenuates isoprenaline HY-108353 -induced cardiac hypertrophic in mouse models.

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