

HY-161663 · 50 mg
MedChemExpress · Cat: HY-161663
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medchemexpress.com/phosphodiesterase-in-2.html
Description
Phosphodiesterase-IN-2 Compound C7 is a selective, orally active inhibitor for phosphodiesterase 10A PDE10A , with an IC50 of 11.9 nM. Phosphodiesterase-IN-2 improves the stability of liver microsomes, and lowers BBB permeability. Phosphodiesterase-IN-2 exhibits good pharmacokinetic characters, and attenuates isoprenaline HY-108353 -induced cardiac hypertrophic in mouse models.







