Phospho-Phospholamban (Ser16) Rabbit Monoclonal Antibody

Description

EnkiLife offers the Phospho-Phospholamban (Ser16) Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB application. Alternative Names of Immunogen: PLN; PLB; Cardiac phospholamban; PLB. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation. Research Area: Signal Transduction