

HY-146159 · 50 mg
MedChemExpress · Cat: HY-146159
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medchemexpress.com/pi3k-hdac-in-2.htmlDescription
PI3K/HDAC-IN-2 is a potent dual PI3K/HDAC inhibitor with IC50s of 226 nM, 279 nM, 467 nM, 29 nM for PI3K?, PI3K?, PI3K?, PI3K?, respectively, and IC50s of 1.3 nM, 3.4 nM, 972 nM, 17 nM, 12 nM for HDAC1, HDAC2, HDC4, HDAC6, HDAC8, respectively. PI3K/HDAC-IN-2 exhibits PI3K? and class I and IIb HDAC selectivity. PI3K/HDAC-IN-2 has remarkable anticancer effects.





