GENERAL CATALOGUE
PI3K/HDAC-IN-3
HY-157295 · 50 mg
MedChemExpress · Cat: HY-157295
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Manufacturer product page
medchemexpress.com/pi3k-hdac-in-3.htmlCatalog No: HY-157295
CAS No: 3006905-22-9
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
PI3K/HDAC-IN-3 36 is a PI3K and HDAC dual inhibitor, with IC50 values of 0.23 nM and 172 nM for PI3K? and HDAC1, respectively. PI3K/HDAC-IN-3 36 suppresses AKT phosphorylation and increased H3 acetylation in MV4-11 cells. PI3K/HDAC-IN-3 36 exhibits significant and dose-dependent anticancer efficacy in a MV4-11 xenograft model.
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