GENERAL CATALOGUE
PI3K?-IN-21
HY-158029 · 50 mg
MedChemExpress · Cat: HY-158029
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medchemexpress.com/pi3k%CE%B1-in-21.html
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Catalog No: HY-158029
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
PI3K?-IN-21 compound 8 is a PI3K? inhibitor, and its selectivity for PI3K? is 10.41/16.99/37.53 times higher than PI3K?/?/? respectively IC50: 96.89/568.24/397.48 nM . PI3K?-IN-21 inhibits cancer cell activity, proliferation, and migration, and induces mitochondrial apoptosis through the PI3K/Akt/mTOR pathway. PI3K?-IN-21 exhibits in vivo antitumor potency in a mouse model of non-small cell lung cancer.
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