GENERAL CATALOGUE
PIC1 PA
HY-P10827 · 1 mg
MedChemExpress · Cat: HY-P10827
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medchemexpress.com/pic1-pa.htmlCatalog No: HY-P10827
CAS No: 1356469-36-7
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
PIC1 PA, a 15 amino-acid peptide, is a potent PIC1 analog that inhibits classical pathway mediated complement activation. PIC1 PA functionally disrupts the C1s-C1r-C1r-C1s/MASPs interaction with collagen-like region CLR of C1q/MBL, respectively. PIC1 PA specifically binds to the CLR of C1q and bounds to purified C1q with a mean equilibrium dissociation constant KD of 33.3 nM.
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