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Piezo1 agonist 1-d2
GENERAL CATALOGUE

Piezo1 agonist 1-d2

HY-169332 · 1 mg

MedChemExpress · Cat: HY-169332

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Catalog No: HY-169332
CAS No: 3058199-62-2
Category: MAPK ERK Pathway
Pack Size: 1 mg
Brand: MedChemExpress

Description

Piezo1 agonist 1-d2 Compound 12a is an agonist for Piezo1 with an EC50 of 2.21 ?M. Piezo1 agonist 1-d2 activates the Ca2+-related ERK signaling pathway, and thus promotes the osteogenic differentiation of bone marrow mesenchymal stem cells BMSCs . Piezo1 agonist 1-d2 ameliorates disuse osteoporosis in the hindlimb-unloading HU rat model.

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