GENERAL CATALOGUE
Pifusertib
HY-19934 · 5 mg
MedChemExpress · Cat: HY-19934
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Catalog No: HY-19934
CAS No: 1402602-94-1
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Pifusertib TAS-117 is a potent, selective, orally active allosteric Akt inhibitor with IC50s of 4.8, 1.6, and 44 nM for Akt1, 2, and 3, respectively . Pifusertib triggers anti-myeloma activities and enhances fatal endoplasmic reticulum ER stress induced by proteasome inhibition. Pifusertib induces apoptosis and autophagy.
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