GENERAL CATALOGUE
Pifusertib hydrochloride
HY-19934A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-19934A
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Manufacturer product page
medchemexpress.com/pifusertib-hydrochloride.htmlCatalog No: HY-19934A
CAS No: 2930090-28-9
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Pifusertib TAS-117 hydrochloride is a potent, selective, orally active allosteric Akt inhibitor with IC50s of 4.8, 1.6, and 44 nM for Akt1, 2, and 3, respectively . Pifusertib hydrochloride triggers anti-myeloma activities and enhances fatal endoplasmic reticulum ER stress induced by proteasome inhibition. Pifusertib hydrochloride induces apoptosis and autophagy.
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