GENERAL CATALOGUE
PIK-C98
HY-12491 · 50 mg
MedChemExpress · Cat: HY-12491
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medchemexpress.com/pik-c98.html
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Catalog No: HY-12491
CAS No: 691388-62-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
PIK-C98 is a potent and selective PI3K inhibitor, with IC50s of 0.59, 1.64, 3.65, and 0.74 ?M for ?, ?, ?, and ? isoforms, respectively. PIK-C98 inhibits all class I PI3Ks but has no effects on AKT or mTOR activity. PIK-C98 interferes with the ATP-binding pockets of PI3Ks by forming H-bonds and arene-H interactions with specific amino acid residues. PIK-C98 induces apoptosis by inhibiting PI3K. PIK-C98 can be used for the research of multiple myeloma.
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