PIM-1/HDAC-IN-1

Name: PIM-1/HDAC-IN-1
Brand: MedChemExpress

HY-143233 · 50 mg

MedChemExpress · Cat: HY-143233

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Manufacturer product page

medchemexpress.com/pim-1-hdac-in-1.html

Catalog No: HY-143233

CAS No: 2897622-19-2

Category: Apoptosis

Pack Size: 50 mg

Brand: MedChemExpress

Description

PIM-1/HDAC-IN-1 compound 4d is a PIM-1 inhibitor, with an IC50 of 343.87 nM. PIM-1/HDAC-IN-1 has strong inhibitory activity and selectivity against HDAC 1 and HDAC 6, with IC50 values of 63.65 and 62.39 nM, respectively. PIM-1/HDAC-IN-1 exhibits apoptosis inducing potential in MCF-7 cell lines. PIM-1/HDAC-IN-1 shows pre-G1 apoptosis and cell cycle arrest at G2/M phase.