GENERAL CATALOGUE
PIM1-IN-1
HY-111552 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-111552
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Manufacturer product page
medchemexpress.com/PIM1-IN-1.htmlCatalog No: HY-111552
CAS No: 1417630-95-5
Category: JAK STAT Signaling
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity.
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