Pitavastatin-d4-1 sodium

Description

Pitavastatin-d4-1 NK-104-d4-1 sodium is the deuterium labeled Pitavastatin sodium HY-B0144B . Pitavastatin NK-104 is a potent hydroxymethylglutaryl-CoA HMG-CoA reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol LDL-C receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects.