Pituitary homeobox 3 Antibody, mAb, Rabbit

Description

Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic mdDA neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.