pJAK2(1001-1013)

Description

pJAK2 1001-1013 is a cell-penetrating peptide that corresponds to the activation loop of JAK2 tyrosine kinase and functions as a SOCS1/3antagonist. pJAK2 1001-1013 blocks SOCS1-mediated negative regulation of immune function, and enhances the biological activity of cytokines such as IFN? and IL6. pJAK2 1001-1013 inhibits the replication of a broad range of viruses and exerts dose-dependent protective efficacy against lethal viral infections. pJAK2 1001-1013 can be used for the study of immune regulation and infection.