GENERAL CATALOGUE
PK11007
HY-128784 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-128784
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Catalog No: HY-128784
CAS No: 874146-69-7
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
PK11007 is a mild thiol alkylator with anticancer activity. PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species ROS levels.
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