GENERAL CATALOGUE
PK68
HY-128348 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-128348
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Catalog No: HY-128348
CAS No: 2173556-69-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
PK68 is a potent orally active and specifical type II inhibitor of receptor-interacting kinase 1 RIPK1 with an IC50 of 90?nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and can be used for the research of inflammatory disorders and cancer metastasis.
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