GENERAL CATALOGUE
PKM2-IN-6
HY-157913 · 5 mg
MedChemExpress · Cat: HY-157913
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medchemexpress.com/pkm2-in-6.htmlCatalog No: HY-157913
CAS No: 771467-00-6
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
PKM2-IN-6 compound 7d is a potent and orally active PKM2 inhibitor with an IC50 value of 23 nM. PKM2-IN-6 induces apoptosis and cell cycle arrest at G2 phase. PKM2-IN-6 reduces the level of PKM1 and PKM2 at the mRNA level. PKM2-IN-6 shows anticancer activity and has the potential for the research of triple-negative breast cancer.
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