GENERAL CATALOGUE
PKM2/PDK1-IN-1
HY-149275 · 50 mg
MedChemExpress · Cat: HY-149275
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medchemexpress.com/pkm2-pdk1-in-1.html
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Catalog No: HY-149275
CAS No: 3041957-90-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
PKM2/PDK1-IN-1, one of shikonin thioether derivatives, is a dual inhibitor of PKM2/PDK1. PKM2/PDK1-IN-1 inhibits the proliferation of NSCLC cells, and induces apoptosis. PKM2/PDK1-IN-1 induces intercellular ROS production, and regulates the apoptotic proteins, to involves in mitochondrial and death receptor pathway.