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PKN1/2-IN-1
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PKN1/2-IN-1

HY-145899 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-145899

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Manufacturer product page

medchemexpress.com/pkn1-2-in-1.html
Catalog No: HY-145899
CAS No: 942425-34-5
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

PKN1/2-IN-1 is a potent cell permeabilizer and selective PKN1/2 inhibitor with IC50 values of 16 nM and 210 nM for PKN1 and PKN2, respectively, and Ki values of 8 nM and 108 nM, respectively. PKN1/2-IN-1 exhibits strong intracellular PKN2 binding capacity in NanoBRET assays IC50 = 2.1 ?M . PKN1/2-IN-1 can be used to study physiological processes such as tumor cell migration.

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