PKN1 Rabbit Monoclonal Antibody

Description

EnkiLife offers the PKN1 Rabbit Monoclonal Antibody. This antibody reacts with Rat species and is suitable for WB application. Alternative Names of Immunogen: DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; PKN-ALPHA. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Research Area: Signal Transduction