

HY-127146 · 250 g
MedChemExpress · Cat: HY-127146
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medchemexpress.com/platensimycin.htmlDescription
Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis IC50=0.1 ?M . Platensimycin targets the ?-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively . Platensimycin is a promising agent for overcoming antibiotic resistance.







