

Z05758 · 100 ug
GenScript · Cat: Z05758
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Manufacturer product page
genscript.com/protein/Z05758-PLAU_uPA_active_form_His_Human....
Description
Plasminogen activator, urokinase uPA is a secreted serine protease, cleaving the sequence Cys-Pro-Gly-Arg560-Val561-Val-Gly-Gly-Cys in plasminogen to form plasmin. Dysregulation of PLAU is often accompanied by various cancers and PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
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