GENERAL CATALOGUE
Plecanatide
HY-108741 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-108741
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Catalog No: HY-108741
CAS No: 467426-54-6
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C GC-C receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis.
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