GENERAL CATALOGUE
PLK1-IN-10
HY-161521 · 50 mg
MedChemExpress · Cat: HY-161521
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Manufacturer product page
medchemexpress.com/plk1-in-10.htmlCatalog No: HY-161521
CAS No: 2991469-21-5
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
PLK1-IN-10 Compound 4Bb is an orally active PLK1 PBD polo-box domain inhibitor. PLK1-IN-10 blocks the interaction of PLK1 with the cell division regulator protein 1 PRC1 and decreases the protein expression of the CDK1-Cyclin B1 complex. PLK1-IN-10 reacts with glutathione GSH to increase cellular oxidative stress, ultimately leading to cell death.
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